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PSC 833
Artikelnummer: Cay20391-1
PSC 833 is a non-immunosuppressant derivative of cyclosporine and potent multidrug-resistance (MDR) modulator. It restores sensitivity of MDR-P388 murine leukemia cells to cytostatic agents when used at concentrations of 70, 33, 45, 34, and 26 nM in combination with colchicine, vincristine (Cay-11764), daunorubicin...
| Schlagworte: | Valspodar, 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A |
| Anwendung: | MDR modulator |
| CAS | 121584-18-7 |
| MW: | 1214.6 D |
ab 53,00 €
Valspodar
Artikelnummer: TGM-T17216-10mg
Description: Valspodar (PSC 833), a specific P-glycoprotein inhibitor and MDR regulator, is commonly used as a chemical sensitizer in the study of advanced epithelial ovarian cancer. Target: P-gp. Smiles:...
| Schlagworte: | PSC 833 |
| Anwendung: | Targets ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] (ABCB1, CD243) |
| CAS | 121584-18-7 |
| MW: | 1214.62 D |
ab 199,00 €
