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RGFP109
Artikelnummer: Cay21568-5
RGFP109 is a brain-penetrant inhibitor of histone deacetylases (HDACs, IC50s = 60 and 50 nM, Kis = 32 and 5 nM for HDAC1 and HDAC3 in cell-free assays, respectively). It has been shown to upregulate frataxin mRNA levels in cultured cells obtained from Friedreich's ataxia patients and in a GAA repeat-based mouse...
| Schlagworte: | RG-2833, N-[6-[(2-aminophenyl)amino]-6-oxohexyl]-4-methyl-benzamide |
| Anwendung: | Brain-penetrant HDAC inhibitor |
| CAS | 1215493-56-3 |
| MW: | 339.4 D |
ab 93,00 €
RG2833
Artikelnummer: TGM-T6639-100mg
Description: RG2833 (RGFP109) (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. Target: HDAC. Smiles: Cc1ccc(cc1)C(=O)NCCCCCC(=O)Nc1ccccc1N. References: Rai M, et al. PLoS One. 2010, 5(1), e8825.
| Schlagworte: | RGFP109 |
| Anwendung: | Brain-penetrant HDAC inhibitor |
| CAS | 1215493-56-3 |
| MW: | 339.43 D |
ab 30,00 €
