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EG 00229 (trifluoroacetate salt)
EG 00229 (trifluoroacetate salt)

Artikelnummer: Cay33937-1

EG 00229 is an antagonist of neuropilin-1 (NRP-1). It inhibits the binding of VEGF-A to porcine aortic endothelial cells expressing NRP-1, but not VEGFR2, with an IC50 value of 8 µM. EG 00229 (100 µM) reduces VEGF-A-induced migration of human umbilical vein endothelial cells (HUVECs) and enhances the cytotoxicity of...
Schlagworte: N2-[[3-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine, 2,2,2-trifluoroacetate
Anwendung: NRP-1 antagonist
CAS 1210945-69-9
MW: 611.6 D
ab 65,00 €
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EG00229
EG00229

Artikelnummer: TGM-T11153-100mg

Description: EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain with an IC50 value of 3 µM. It does not affect the binding of VEGF-A to other receptors, such as VEGFR-1 and VEGFR-2. Target: Others. Smiles:...
CAS 1210945-69-9
MW: 611.6 D
ab 43,00 €
Bewerten