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N6022
Artikelnummer: Cay21269-10
N6022 is a tight-binding, specific, and fully reversible inhibitor of S-nitrosoglutathione reductase (GSNOR, IC50 = 8 nM, Ki = 2.5 nM). It is reported to bind in the GSNO substrate binding pocket like a competitive inhibitor, although in kinetic assays it behaves with a mixed uncompetitive mode of inhibition toward...
| Schlagworte: | 1-[4-(aminocarbonyl)-2-methylphenyl]-5-[4-(1H-imidazol-1-yl)phenyl]-1H-pyrrole-2-propanoic acid |
| Anwendung: | GSNOR (ADH5) inhibitor |
| CAS | 1208315-24-5 |
| MW: | 414.5 D |
ab 45,00 €
N6022
Artikelnummer: TGM-T6901-100mg
Description: N6022(IC50 of 8 nM) is an effective, reversible, and selective S-Nitrosoglutathione reductase(GSNOR) inhibitor. Target: GSNOR. Smiles: Cc1cc(ccc1-n1c(CCC(O)=O)ccc1-c1ccc(cc1)-n1ccnc1)C(N)=O. References: Green LS, et al. Biochemistry. 2012, 51(10), 2157-2168
| Anwendung: | GSNOR (ADH5) inhibitor |
| CAS | 1208315-24-5 |
| MW: | 414.46 D |
ab 39,00 €
