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MK-1064
Artikelnummer: TGM-T3722-100mg
Description: MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA). Target: OX Receptor. Smiles: COc1ccc(CNC(=O)c2cc(cnc2-c2ccccn2)-c2cncc(Cl)c2)nc1OC. References: Roecker AJ et al. ChemMedChem. 2014 Feb,9(2):311-22.
| Schlagworte: | MK 1064, Urokinase inhibitor 1 |
| Anwendung: | Orexin OX2 receptor antagonist |
| CAS | 1207253-08-4 |
| MW: | 461.9 D |
ab 48,00 €
MK-1064
Artikelnummer: Cay20993-1
MK-1064 is an orexin 2 receptor (OX2R) antagonist that is selective for OX2R over OX1R (IC50s = 18 and 1,789 nM, respectively). It decreases the amount of time spent in active wake and increases the time spent in rapid eye movement (REM) sleep and slow-wave sleep (SMS) in mice, rats, dogs, and rhesus monkeys when...
| Schlagworte: | 5''-chloro-N-[(5,6-dimethoxy-2-pyridinyl)methyl]-[2,2':5',3''-terpyridine]-3'-carboxamide |
| Anwendung: | Orexin OX2 receptor antagonist |
| CAS | 1207253-08-4 |
| MW: | 461.9 D |
ab 52,00 €
