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PKC 412
Artikelnummer: Cay10459-1
PKC 412 is a cell-permeable, reversible inhibitor of several serine/threonine and tyrosine kinases, including conventional PKC isoforms (alpha, beta, and gamma), Syk, FLK1, Akt, PKA, c-Kit, C-Fgr, c-Src, FLT3, PDFRbeta, VEGFR1, and VEGFR2 with IC50 values ranging from 80-500 nM. It also upregulates the expression of...
| Schlagworte: | CGP 41231, CGP 41251, Midostaurin, N-Benzoylstaurosporine,... |
| Anwendung: | Kinase inhibitor |
| CAS | 120685-11-2 |
| MW: | 570.6 D |
ab 42,00 €
PKC412 (4'-N-Benzoyl Staurosporine, CGP 41251, Midostaurin)
Artikelnummer: P4210-63.1
The staurosporine analog, PKC412, inhibits a variety of serine/threonine and tyrosine kinases including PKC (IC50=50nM), cyclic AMP-dependent protein kinase (IC50=2.4uM), S6 kinase (IC50=5.0uM), and EGFR (epidermal growth factor receptor) tyrosine-kinase activity (IC50=3.0uM). CAS Number: 120685-11-2, Molecular...
| CAS | 120685-11-2 |
| MW: | 570.64 |
ab 303,00 €
Midostaurin
Artikelnummer: TGM-T3211-100mg
Description: PKC412(Midostaurin (PKC412), CGP41231, CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3)...
| Schlagworte: | CGP41231, CGP 41251, N-Benzoylstaurosporine, PKC412 |
| Anwendung: | Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135) |
| CAS | 120685-11-2 |
| MW: | 570.64 D |
ab 45,00 €
