Zu "1206161-97-8" wurden 4 Artikel gefunden!
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Filgotinib
Artikelnummer: Cay17669-5
Filgotinib is a JAK1 inhibitor (IC50 = 10 nM). It is selective for JAK1 over JAK3 (IC50 = 810 nM) but also inhibits JAK2 and tyrosine kinase 2 (Tyk2, IC50s = 28 and 116 nM, respectively), as well as Abl, FLT1, -3, and -4, FMS, Mer, and TBK1 activity by greater than 35% in a panel of 177 tyrosine kinases at 1 µM....
| Schlagworte: | GLPG0634,... |
| Anwendung: | JAK1 inhibitor |
| CAS | 1206161-97-8 |
| MW: | 425.5 D |
ab 87,00 €
GLPG0634
Artikelnummer: SYN-1158-M001
Soluble in DMSO. GLPG0634 is a novel and specific inhibitor of JAK1 and JAK2 with IC(50) of 10nM and 28nM respectively measured by in vitro kinase assays (ATP 2µM). In particular GLPG0634, while being a potent inhibitor of JAK1 and JAK2 does not inhibit TYK2 or JAK3, and GLPG0634 exhibits a dramatically improved in...
| Schlagworte: | GLPG-0634, Filgotinib |
| Anwendung: | JAK1 / JAK2 inhibitor |
| CAS | 1206161-97-8 |
| MW: | 425,5 D |
ab 293,00 €
GLPG-0634
Artikelnummer: LKT-G4662.1
JAK1 inhibitor.
| Schlagworte: | GLPG0634, Filgotinib |
| Anwendung: | JAK1 inhibitor |
| CAS | 1206161-97-8 |
| MW: | 425.5 D |
ab 157,00 €
NEU
Filgotinib
Artikelnummer: TGM-T1929-100mg
Description: Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 values of 10 nM for JAK1, 28 nM for JAK2, 810 nM for JAK3, and 116 nM for TYK2. Target: Tyrosine Kinases, JAK. Smiles: O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1. References: Van Rompaey L, et al. J Immunol. 2013, 191(7), 3568-3577.
| Schlagworte: | GLPG0634 |
| Anwendung: | Targets Janus kinase 1 [EC:2.7.10.2] (JAK1) |
| CAS | 1206161-97-8 |
| MW: | 425.5 D |
ab 67,00 €
