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ThioLox
Artikelnummer: Cay38946-10
ThioLox is an inhibitor of 15-lipoxygenase 1 (15-LO-1, Ki = 3.3 µM). It also is an inhibitor of P. falciparum aspartate carbamoyltransferase (IC50 = 3.32 µM). ThioLox (50 µM) reduces LPS-induced expression of the mRNAs encoding TNF-alpha, inducible nitric oxide synthase (iNos), Il-1beta, Il-6, Il-8, and Il-12b in...
| Schlagworte: | 2-amino-N-butyl-5-phenyl-3-thiophenecarboxamide |
| Anwendung: | 15-LOX-1 (ALOX15) inhibitor |
| CAS | 1202193-89-2 |
| MW: | 274.4 D |
ab 89,00 €
ThioLox
Artikelnummer: TGM-T67908-100mg
Description: ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with an IC50 value of 12 µM, demonstrating significant anti-inflammatory and neuroprotective properties, including strong protection against glutamate toxicity. Target: Lipoxygenase. Smiles: C(NCCCC)(=O)C=1C=C(SC1N)C2=CC=CC=C2. References:...
| Anwendung: | 15-LOX-1 (ALOX15) inhibitor |
| CAS | 1202193-89-2 |
| MW: | 274.38 D |
ab 30,00 €
