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Tenidap
Artikelnummer: Cay17413-10
Tenidap is a COX-1 selective non-steroidal anti-inflammatory drug (IC50s = 30 µM for COX-1, COX-2, and 5-lipoxygenase (5-LO), respectively). It has anti-inflammatory and antirheumatic properties. In vitro, it inhibits prostaglandin D2 (PGD2), leukotriene B4 (LTB4), and prostaglandin E2 (PGE2) synthesis (IC50s =...
| Schlagworte: | CP 66,248, (3Z)-5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide |
| Anwendung: | Antiinflammatory |
| CAS | 120210-48-2 |
| MW: | 320.8 D |
ab 53,00 €
Tenidap
Artikelnummer: TGM-T17036-100mg
Description: Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities. Target: DNA/RNA Synthesis, COX. Smiles: NC(=O)N1C(=O)\C(=C(/O)c2cccs2)c2cc(Cl)ccc12. References: Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual...
| Schlagworte: | CP-66248 |
| Anwendung: | Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1) |
| CAS | 120210-48-2 |
| MW: | 320.75 D |
ab 30,00 €
