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CBL0137 (hydrochloride)
Artikelnummer: Cay19373-10
Curaxins are small molecules that simultaneously activate p53 and inhibit NF-kappaB without causing detectable genotoxicity. CBL0137 is a water soluble and metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-kappaB with an EC50 value of 0.47 µM. It functionally inactivates...
| Schlagworte: | CBLC137, Curaxin 137, 1,1'-[9-[2-[(1-methylethyl)imino]ethyl]-9H-carbazole-3,6-diyl]bis-ethanone, monohydrochloride |
| Anwendung: | Curaxin, p53 activator, NF-kappaB inhibitor |
| CAS | 1197397-89-9 |
| MW: | 372.9 D |
ab 168,00 €
CBL0137 hydrochloride
Artikelnummer: TGM-T4361-100mg
Description: CBL0137 hydrochloride (Curaxin-137 hydrochloride) activates p53 and inhibits NF-kB (EC50: 0.37/0.47 µM) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT. Target: Others, NF-kappaB, p53. Smiles: Cl.CC(C)NCCn1c2ccc(cc2c2cc(ccc12)C(C)=O)C(C)=O....
| Schlagworte: | CBLC137, Curaxin 137, CBL0137, CBL-C137 hydrochloride, Curaxin-137 hydrochloride |
| Anwendung: | Curaxin, p53 activator, NF-kappaB inhibitor |
| CAS | 1197397-89-9 |
| MW: | 372.88 D |
ab 41,00 €
