Zu "1194961-19-7" wurden 3 Artikel gefunden!
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PRT-060318
Artikelnummer: TGM-T6957-1mg
Description: PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment. Target: Syk. Smiles: Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)ncc2C(N)=O)c1. References: Reilly MP, et al. Blood. 2011, 117(7):2241-2246.
| Schlagworte: | PRT-060318 2HCl, PRT318, P142-76 |
| Anwendung: | Syk inhibitor |
| CAS | 1194961-19-7 |
| MW: | 340.42 D |
ab 34,00 €
PRT060318
Artikelnummer: Cay22476-10
PRT060318 is a potent and selective inhibitor of spleen tyrosine kinase (Syk, IC50 = 4 nM). It is selective, inhibiting 92% of Syk activity, while other kinases retain >70% activity, at a concentration of 50 nM in a panel of 270 kinases. PRT060318 inhibits convulxin-induced aggregation of human platelet-rich plasma...
| Schlagworte: | P142-76, PRT318, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(3-methylphenyl)amino]-5-pyrimidinecarboxamide |
| Anwendung: | Syk inhibitor |
| CAS | 1194961-19-7 |
| MW: | 340.4 D |
ab 215,00 €
PRT-060318
Artikelnummer: SYN-1204-M001
Soluble in DMSO. PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model. Target: Syk , Kinase Group: PTK , Substrate: Tyrosine
| Schlagworte: | PRT060318 |
| Anwendung: | Syk inhibitor |
| CAS | 1194961-19-7 |
| MW: | 340,4 D |
ab 231,00 €
