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Cipargamin
Artikelnummer: Cay30678-1
Cipargamin is an antimalarial agent. It inhibits the Na+-ATPase activity of wild-type or mutant P. falciparum P-type ATPase (PfATP4, IC50s = 12.3-13.9 and 21.1-32.5 nM, respectively, in P. falciparum membranes). Cipargamin is active against the P. falciparum chloroquine-sensitive strain NF54 and...
| Schlagworte: | KAE609, NITD609,... |
| Anwendung: | Antimalarial agent |
| CAS | 1193314-23-6 |
| MW: | 390.2 D |
ab 123,00 €
Cipargamin
Artikelnummer: TGM-T16326-100mg
Description: Cipargamin (NITD609) is an effective antimalarial compound. It has an IC50 of appr 1 nM against P. falciparum. Target: Parasite. Smiles: O=C1[C@]2(C3=C(C=4C(N3)=CC(Cl)=C(F)C4)C[C@H](C)N2)C=5C(N1)=CC=C(Cl)C5. References: Zhou Y, et al. Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of...
| Schlagworte: | NITD609, KAE609 |
| CAS | 1193314-23-6 |
| MW: | 390.24 D |
ab 31,00 €
