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MRT68921
Artikelnummer: TGM-T6899-100mg
Description: MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively. Target: Autophagy. Smiles: N(CCCNC(=O)C1CCC1)C=2C(=CN=C(NC=3C=C4C(=CC3)CN(C)CC4)N2)C5CC5. References: Petherick KJ, et al. J Biol Chem. 2015, 290(18), 11376-11383.
| Schlagworte: | MRT68921 HCl |
| Anwendung: | Cell-permeable, potent, specific ULK1 & ULK2 inhibitor |
| CAS | 1190379-70-4 |
| MW: | 434.58 D |
ab 37,00 €
MRT68921
Artikelnummer: Cay19905-1
MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively). Through its effects on ULK1, MRT68921 blocks autophagy in cells, driving the accumulation of stalled early autophagosomal structures.Formal Name:...
| Schlagworte: | N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxa... |
| Anwendung: | Cell-permeable, potent, specific ULK1 & ULK2 inhibitor |
| CAS | 1190379-70-4 |
| MW: | 434.6 D |
ab 44,00 €
