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N-Carbamyl-L-Glutamic Acid
N-Carbamyl-L-Glutamic Acid

Artikelnummer: Cay23512-1

N-Carbamyl-L-glutamic acid is an activator of carbamoyl phosphate synthetase 1 (CPS1), the first enzyme in the urea cycle. It is a structural analog of N-acetyl-glutamate, an endogenous CPS1 activator. N-Carbamyl-L-glutamic acid (500 mg/kg) reduces 2-ketoisocaproate-induced hyperammonemia in a mouse model of...
Schlagworte: Carglumic Acid, N-(aminocarbonyl)-L-glutamic acid
Anwendung: Carbamoyl phosphate synthetase 1 (CPS1) activator
CAS 1188-38-1
MW: 190.2 D
ab 67,00 €
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Carglumic Acid
Carglumic Acid

Artikelnummer: TGM-T0755-1g

Description: Carglumic Acid (Ureidoglutaric acid) is an orphan drug used to treat hyperammonemia in patients with N-acetyl glutamate synthase absence. This rare hereditary disease results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and lead to neurologic problems, coma,...
Schlagworte: N-Carbamylglutamate, Carbaglu, N-Carbamyl-L-glutamic acid, Ureidoglutaric acid, Carbamino-L-glutamic acid,...
CAS 1188-38-1
MW: 190.15 D
ab 46,00 €
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