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UK-122 TFA salt
Artikelnummer: TGM-T29051-10mg
Description: UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol/L) but significantly inhibited the migration and invasion of this pancreatic cancer cell...
| Schlagworte: | UK-122, K122 trifloroacetic acid, UK 122, UK122 TFA salt, UK122, uPA Inhibitor II |
| Anwendung: | Urokinase-type plasminogen activator (uPA) inhibitor |
| CAS | 1186653-73-5 |
| MW: | 405.33 D |
ab 187,00 €
UK 122 (trifluoroacetate salt)
Artikelnummer: Cay9001218-1
UK 122 is an inhibitor of urokinase-type plasminogen activator (uPA, IC50 = 0.2 µM). It is selective for uPA over tissue-type plasminogen activator (tPA), trypsin, plasmin, and thrombin (IC50s = >100 µM for all). UK 122 (100 µM) inhibits the migration and invasion of CFPAC-1 pancreatic cancer cells. It prevents...
| Schlagworte: | 4-[(E)-(5-oxo-2-phenyl-4(5H)-oxazolylidene)methyl]-benzenecarboximidamide, 2,2,2-trifluoroacetate |
| Anwendung: | Urokinase-type plasminogen activator (uPA) inhibitor |
| CAS | 1186653-73-5 |
| MW: | 405.3 D |
ab 103,00 €
