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MK2-IN-3 hydrate
Artikelnummer: TGM-T12058-100mg
Description: MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM). Target: MAPK, ERK, MNK. Smiles: O=C1C2=C(NC(C3=CC(C4=CC5=CC=CC=C5N=C4)=NC=C3)=C2)CCN1.[H]O[H]. References: Anderson DR, et al. Pyrrolopyridine inhibitors of...
| Schlagworte: | MK-2 Inhibitor III |
| Anwendung: | Potent, cell-permeable MAPKAPK2 inhibitor |
| CAS | 1186648-22-5 |
| MW: | 358.39 D |
ab 31,00 €
MK2 Inhibitor III
Artikelnummer: Cay15943-5
MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM). It...
| Schlagworte: | 1,5,6,7-tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one, monohydrate |
| Anwendung: | Potent, cell-permeable MAPKAPK2 inhibitor |
| CAS | 1186648-22-5 |
| MW: | 358.4 D |
ab 100,00 €
