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AP-III-a4
Artikelnummer: TGM-T6759-100mg
Description: AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 µM. Target: Glucokinase. Smiles: NCCOCCOCCNC(=O)Cc1ccc(Nc2nc(NCC3CCCCC3)nc(NCc3ccc(F)cc3)n2)cc1. References: Jung DW, et al. ACS Chem Biol. 2013, 8(6), 1271-1282.
| Schlagworte: | ENOblock |
| Anwendung: | Enolase inhibitor |
| CAS | 1177827-73-4 |
| MW: | 594.72 D |
ab 46,00 €
AP-III-a4
Artikelnummer: Cay19933-1
AP-III-a4 is a small molecule enolase inhibitor (IC50 = 0.576 µM) that inhibited cancer cell metastasis in an in vivo zebrafish cancer cell xenograft model. It also reduced hyperglycemia and hyperlipidemia in C57BL/Ksj-db/db mice, a transgenic model of type 2 diabetes. Another study found that AP-III-a4 did not...
| Schlagworte: | ENOblock,... |
| Anwendung: | Enolase inhibitor |
| CAS | 1177827-73-4 |
| MW: | 594.7 D |
ab 98,00 €
AP-III-a4 . HCl
Artikelnummer: AG-CR1-3696-M001
Cell permeable first non-substrate analog enolase inhibitor (IC50=0.576µM). A recent study suggested no direct blocking of enolase activity in vitro and a indirect mechanism. Useful agent for immunometabolism research. The glycolysis enzymes enolase is known to have additional, non-glycolytic roles in cellular...
| Schlagworte: | ENOblock |
| Anwendung: | Enolase inhibitor |
| CAS | 1177827-73-4 |
| MW: | 631.2 D |
ab 77,00 €
