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BMS 794833
Artikelnummer: Cay26180-1
BMS 794833 is an inhibitor of c-Met and VEGF receptor 2 (VEGFR2) with IC50 values of 1.7 and 15 nM, respectively, that also inhibits Axl, Flt3, and Ron. It inhibits proliferation of GTL-16 gastric carcinoma cells (IC50 = 39 nM) and induces tumor statsis in GTL-16 and U87 mouse xenograft models when administered at a...
| Schlagworte: | N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-pyridinecarboxamide |
| Anwendung: | c-Met inhibitor, VEGFR2 inhibitor |
| CAS | 1174046-72-0 |
| MW: | 468.8 D |
ab 56,00 €
BMS-794833
Artikelnummer: LKT-B4976.1
MET, VEGFR2, Ron, Axl, FLT3 inhibitor.
| Schlagworte: | BMS794833 |
| Anwendung: | c-Met inhibitor, VEGFR2 inhibitor |
| CAS | 1174046-72-0 |
| MW: | 468.84 D |
ab 75,00 €
BMS-794833
Artikelnummer: TGM-T2419-100mg
Description: BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2, a prodrug of BMS-817378. Target: VEGFR, c-Met/HGFR. Smiles: Nc1nccc(Oc2ccc(NC(=O)c3c[nH]cc(-c4ccc(F)cc4)c3=O)cc2F)c1Cl
| CAS | 1174046-72-0 |
| MW: | 468.84 D |
ab 33,00 €
