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CI-976
Artikelnummer: Cay17235-5
Acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT-1) is a sterol O-acyltransferase that catalyzes the formation of fatty acid-cholesterol esters, an important step in lipoprotein assembly and dietary cholesterol absorption. CI-976 is a potent, selective inhibitor of ACAT-1 (IC50 = 73 nM). It is orally bioavailable...
| Schlagworte: | PD 128042, 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide |
| Anwendung: | ACAT-1 inhibitor |
| CAS | 114289-47-3 |
| MW: | 393.6 D |
ab 110,00 €
PD 128042
Artikelnummer: TGM-T22665-100mg
Description: PD 128042 (CI 976) is a potent, orally active, and selective ACAT inhibitor (IC50: 73 nM) as well as a lysophospholipid acyltransferase (LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 µM) and multiple membrane trafficking steps. Target: Acyltransferase. Smiles:...
| Schlagworte: | CI 976 |
| Anwendung: | ACAT-1 inhibitor |
| CAS | 114289-47-3 |
| MW: | 393.56 D |
ab 30,00 €
