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VU0255035
Artikelnummer: Cay19353-10
VU0255035 is a competitive, orthosteric antagonist of the muscarinic M1 receptor (IC50 = 130 nM). It displays at least 75-fold selectivity for M1 over other muscarinic receptors, as well as a panel of receptors, ion channels, and transporters. VU0255035 is effective in cells and in vivo and brain penetrating,...
| Schlagworte: | ML-012, N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide |
| Anwendung: | Muscarinic M1 receptor antagonist |
| CAS | 1135243-19-4 |
| MW: | 432.5 D |
ab 216,00 €
VU 0255035
Artikelnummer: TGM-T23508-100mg
Description: VU 0255035 is a highly selective, competitive, and brain-penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM, used to reduce pilocarpine-induced seizures in mice and to examine the role of the M1 receptor in diverse situations. Target: AChR. Smiles:...
| CAS | 1135243-19-4 |
| MW: | 432.52 D |
ab 31,00 €
