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VER-155008
Artikelnummer: Cay17257-10
VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70, IC50 = 0.5 µM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 µM) and glucose-regulated protein 78 (Grp78, KD = 80 nM). VER-155008...
| Schlagworte: | 5'-O-[(4-cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine |
| Anwendung: | HSP70 inhibitor |
| CAS | 1134156-31-2 |
| MW: | 556.4 D |
ab 139,00 €
VER-155008
Artikelnummer: TGM-T7010-100mg
Description: VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 µM, 2.6 µM, and 2.6 µM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90. Target: Autophagy, HSP, GPR. Smiles:...
| Schlagworte: | VER155008 |
| Anwendung: | Potent HSP70 inhibitor, apoptosis inducer |
| CAS | 1134156-31-2 |
| MW: | 556.4 D |
ab 38,00 €
