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Dasabuvir
Artikelnummer: TGM-T3489-100mg
Description: Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase. Upon administration and intracellular uptake, dasabuvir binds HCV NS5B polymerase, blocking viral RNA synthesis and replication. The HCV NS5B protein is...
| Schlagworte: | ABT-333 |
| Anwendung: | Targets Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48] (NS5B) |
| CAS | 1132935-63-7 |
| MW: | 493.57 D |
ab 34,00 €
ABT-333
Artikelnummer: Cay18482-10
ABT-333 is an inhibitor of hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp, IC50s = 0.0022-0.0107 µM for genotypes 1a and 1b). It is selective for HCV genotype 1 polymerases over genotypes 2, 3, and 4 (IC50s = 0.9->20 µM), as well as human polymerases (IC50s = >100 µM). Formulations containning ABT-333,...
| Schlagworte: | Dasabuvir,... |
| Anwendung: | Antiviral, NS5B polymerase inhibitor |
| CAS | 1132935-63-7 |
| MW: | 493.5 D |
ab 61,00 €
