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AZ 3146
Artikelnummer: Cay19991-10
AZ 3146 is an inhibitor of the monopolar spindle 1 (Mps1) checkpoint kinase (IC50 = 35 nM). It displays selectivity over 46 other kinases including Cdk1 and Aurora kinase B. It has been shown to inhibit the recruitment of Mad1, Mad2, and centromere protein E (CENP-E) to kinetochores. AZ 3146 can be used with...
| Schlagworte: | Mps1 Inhibitor III,... |
| Anwendung: | TTK / Mps1 inhibitor |
| CAS | 1124329-14-1 |
| MW: | 452.6 D |
ab 164,00 €
AZ3146
Artikelnummer: TGM-T2689-100mg
Description: AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM. Target: Kinesin. Smiles: O=C1N(C=2C(N1C)=CN=C(NC3=C(OC)C=C(OC4CCN(C)CC4)C=C3)N2)C5CCCC5. References: Hewitt L, et al. J Cell Biol, 2010, 190(1), 25-34.
| Schlagworte: | AZ 3146 |
| CAS | 1124329-14-1 |
| MW: | 452.55 D |
ab 34,00 €
