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Sitravatinib
Artikelnummer: Cay27338-5
Sitravatinib is a multi-kinase inhibitor. It inhibits 35 kinases (IC50s = 0.5-5,550 nM) in a panel of 55 receptor tyrosine kinases (RTKs). Sitravatinib reduces proliferation of A-673, LPS141, MPNST, DDLS, and Saos-2 cancer cells (IC50s = 1,750, 340.1, 705.7, 266, and 1,830 nM, respectively) and decreases...
| Schlagworte: | MGCD-516,... |
| Anwendung: | Multi-kinase inhibitor, receptor tyrosine kinase inhibitor |
| CAS | 1123837-84-2 |
| MW: | 629.7 D |
ab 85,00 €
Sitravatinib
Artikelnummer: TGM-T4349-100mg
Description: Sitravatinib (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRalpha/beta, PDGFR, and Axl. Target: VEGFR, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor, FLT, Discoidin Domain Receptor (DDR). Smiles:...
| Schlagworte: | MG516, MGCD516 |
| Anwendung: | Targets AXL receptor tyrosine kinase [EC:2.7.10.1] (AXL, UFO) |
| CAS | 1123837-84-2 |
| MW: | 629.68 D |
ab 45,00 €
