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PF-299804
Artikelnummer: Cay9001879-1
The epidermal growth factor receptors (EGFR), whose members include ErbB1 (HER1), ErbB2 (HER2), ErbB3 (HER3), and ErbB4 (HER4), are receptor tyrosine kinases that are often over-expressed in cancer. PF-299804 is a second generation pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1,...
| Schlagworte: | Dacomitinib, PF299, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-(2E)-butenamide |
| Anwendung: | pan-erbB receptor tyrosine kinase inhibitor |
| CAS | 1110813-31-4 |
| MW: | 469.9 D |
ab 68,00 €
Dacomitinib Anhydrous
Artikelnummer: LKT-D004098.100
EGFR inhibitor.
| Schlagworte: | PF00299804 Anhydrous |
| Anwendung: | EGFR / ERBB2 (HER2) / ERBB4 (HER4) inhibitor |
| CAS | 1110813-31-4 |
| MW: | 469.95 D |
ab 85,00 €
Dacomitinib
Artikelnummer: TGM-T2483-100mg
Description: Dacomitinib (PF299)(PF299804, PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively. Target: EGFR, Apoptosis. Smiles:...
| Schlagworte: | PF-00299804, PF-299804, PF299 |
| Anwendung: | Targets epidermal growth factor receptor [EC:2.7.10.1] (EGFR, ERBB1) |
| CAS | 1110813-31-4 |
| MW: | 469.94 D |
ab 31,00 €
