Zu "1108743-60-7" wurden 3 Artikel gefunden!
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Entrectinib
Artikelnummer: Cay19476-1
Entrectinib is an inhibitor of TrkA (IC50 = 1.7 nM), TrkB (IC50 = 0.1 nM), and TrkC (IC50 = 0.1 nM), as well as C-ros oncogene 1 (ROS1, IC50 = 0.2 nM) and anaplastic lymphoma kinase (ALK, IC50 = 1.6 nM). Entrectinib blocks proliferation of ALK-dependent cell lines, including those with L1196M or C1156Y resistance...
| Schlagworte: | NMS-E628, RXDX-101,... |
| Anwendung: | TrkA/B/C inhibitor |
| CAS | 1108743-60-7 |
| MW: | 560.6 D |
ab 54,00 €
NMS-E628
Artikelnummer: LKT-N4974.1
ALK and Ros1 inhibitor, Trk antagonist.
| Schlagworte: | Entrectinib, RXDX-101 |
| Anwendung: | ALK and Ros1 inhibitor, Trk antagonist |
| CAS | 1108743-60-7 |
| MW: | 560.64 D |
ab 94,00 €
Entrectinib
Artikelnummer: TGM-T3678-100mg
Description: Entrectinib (RXDX-101) is a Trk, ROS1, and ALK inhibitor that inhibits TrkA, TrkB, TrkC, ROS1, and ALK (IC50=1/3/5/12/7 nM) with oral activity and blood-brain-barrier penetration. Entrectinib exhibits both antitumor and CNS activity. Target: ALK, ROS Kinase, ROS, Autophagy, Trk receptor. Smiles:...
| Schlagworte: | RXDX-101, NMS-E628 |
| Anwendung: | Targets neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1] (NTRK1, TRKA) |
| CAS | 1108743-60-7 |
| MW: | 560.64 D |
ab 34,00 €
