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ITD 1
ITD 1

Artikelnummer: Cay23326-10

ITD 1 is an inhibitor of TGF-beta (IC50 = 0.85 µM). It is selective for TGF-beta in an SBE4/Smad reporter assay, providing 83% inhibition when used at a concentration of 2.5 µM, over activin A, which is inhibited by 51% when used at the same concentration. ITD 1 inhibits TGF-beta signaling by induction of TGF-beta...
Schlagworte: 4-[1,1'-biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid, ethyl ester
Anwendung: TGF-beta inhibitor, TGF-beta receptor type II degradation inducer
CAS 1099644-42-4
MW: 415.5 D
ab 139,00 €
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ITD-1
ITD-1

Artikelnummer: TGM-T2273-100mg

Description: ITD-1 is a potent and highly selective TGFbeta pathway inhibitor. Target: TGF-beta/Smad. Smiles: CCOC(=O)C1=C(C)NC2=C(C1c1ccc(cc1)-c1ccccc1)C(=O)CC(C)(C)C2. References: Willems E, et al. Cell Stem Cell. 2012 Aug 3,11(2):242-252.
Anwendung: TGF-beta inhibitor, TGF-beta receptor type II degradation inducer
CAS 1099644-42-4
MW: 415.52 D
ab 32,00 €
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