Zu "1096708-71-2" wurden 3 Artikel gefunden!
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TAK-580
Artikelnummer: TGM-T6895-100mg
Description: TAK-580 (MLN2480) is an oral, selective pan-Raf kinase inhibitor in Clinicalal trials. Target: Raf. Smiles: CC(NC(=O)c1ncnc(N)c1Cl)c1ncc(s1)C(=O)Nc1cc(c(Cl)cn1)C(F)(F)F. References: Elizabeth Grace Carideo Cunniff, et al. Journal of Clinical Oncology. 2013:e13529.
| Schlagworte: | MLN2480, BIIB-024 |
| Anwendung: | Targets B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] (BRAF) |
| CAS | 1096708-71-2 |
| MW: | 506.29 D |
ab 48,00 €
MLN2480
Artikelnummer: Cay19675-1
MLN2480 is an orally bioavailable pan-Raf kinase inhibitor that inhibits MAP kinase pathway signaling in BRAF-mutant melanoma models. It shows antitumor activity in melanoma, colon, lung, and pancreatic cancer xenograft models. MLN2480 demonstrates synergistic activity with TAK-733, an allosteric MEK kinase...
| Schlagworte: | BIIB-024, TAK-580,... |
| Anwendung: | Selective pan-Raf inhibitor |
| CAS | 1096708-71-2 |
| MW: | 506.3 D |
ab 62,00 €
MLN2480
Artikelnummer: LKT-M4452.1
MLN 2480 is an oral, selective pan-Raf kinase inhibitor in chinical trials.
| Schlagworte: | BIIB-024,... |
| Anwendung: | pan-Raf inhibitor |
| CAS | 1096708-71-2 |
| MW: | 506.3 D |
ab 207,00 €
