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JNJ-31020028
Artikelnummer: Cay18407-25
JNJ-31020028 is a brain-permeable selective antagonist of the neuropeptide Y (NPY) receptor Y2 (IC50s = 8.51, 6.03, and 6.17 nM for human, rat, and mouse receptors, respectively) with over 100-fold selectivity for Y2 over Y1, Y4, and Y5 receptors. JNJ-31020028 inhibits calcium release induced by peptide YY in a...
| Schlagworte: | N,N-diethyl-4-[2-fluoro-4-[[2-(3-pyridinyl)benzoyl]amino]phenyl]-alpha-phenyl-1-piperazineacetamide |
| Anwendung: | NPY2R antagonist |
| CAS | 1094873-14-9 |
| MW: | 565.7 D |
ab 105,00 €
JNJ-31020028
Artikelnummer: TGM-T1997-100mg
Description: JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human, pIC50=8.22, rat), it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors. Target: Neuropeptide Y Receptor. Smiles:...
| Schlagworte: | JNJ 31020028 |
| CAS | 1094873-14-9 |
| MW: | 565.68 D |
ab 41,00 €
