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UCM05
Artikelnummer: Cay19090-5
UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 µM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of...
| Schlagworte: | G28UCM, 3,4,5-trihydr3,4,5-trihydroxy-benzoic acid 1,1'-(1,3-naphthalenediyl) ester |
| Anwendung: | Fatty acid synthase inhibitor |
| CAS | 1094451-90-7 |
| MW: | 464.4 D |
ab 44,00 €
UCM05
Artikelnummer: TGM-T21831-100mg
Description: UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including cell lines resistant to anti-HER2 drugs [1]. Additionally, it functions as an inhibitor of the Filamentous temperature-sensitive protein Z (FtsZ), selectively inhibiting the...
| Schlagworte: | G28UCM |
| CAS | 1094451-90-7 |
| MW: | 464.38 D |
ab 34,00 €
