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I-OMe-Tyrphostin AG 538
Artikelnummer: TGM-T11593-100mg
Description: I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kalpha (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-deficient PANC1 cells. Target: PI3K, IGF-1R. Smiles:...
| Schlagworte: | I-OMe-AG 538 |
| CAS | 1094048-77-7 |
| MW: | 437.19 D |
ab 48,00 €
I-OMe AG-538
Artikelnummer: Cay35090-1
An IGF-1R and PI5P4Ka inhibitor (IC50s = 3.4 and 1 µM, respectively), selectively cytotoxic to nutrient-deprived PANC-1 cells over nutrient-sufficient PANC-1 cells. Formulation: A solid. InChI: InChI=1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+....
| Schlagworte: | I-OMe Tyrphostin AG-538, 3,4-dihydroxy-aE-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]-beta-oxo-benzenepropanenitrile |
| Anwendung: | IGF-1R / PI5P4Ka inhibitor |
| CAS | 1094048-77-7 |
| MW: | 437.2 D |
ab 45,00 €
