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GRL0617
Artikelnummer: TGM-T11464-100mg
Description: GRL0617 is a selective and competitive noncovalent inhibitor of SARS-CoVPLpro and deubiquitinase (IC50: 0.6 µM, Ki: 0.49 µM). Target: SARS-CoV, DUB. Smiles: C[C@@H](NC(=O)c1cc(N)ccc1C)c1cccc2ccccc12. References: Ratia K, et al. A noncovalent class of papain-like protease/deubiquitinase inhibitors...
| CAS | 1093070-16-6 |
| MW: | 304.39 D |
ab 31,00 €
COVID-19 Forschung
GRL-0617
Artikelnummer: Cay33348-1
GRL-0617 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 papain-like proteases (PLpros, IC50s = 0.6 and 1.5 µM, respectively). It increases the viability of SARS-CoV-infected Vero E6 cells (EC50 = 14.5 µM). GRL-0617 (6.25-50 µM) reduces viral replication in...
| Schlagworte: | 5-amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-benzamide |
| Anwendung: | SARS-CoV and SARS-CoV-2 PLpro inhibitor |
| CAS | 1093070-16-6 |
| MW: | 304.4 D |
ab 45,00 €
