Zu "1088991-73-4" wurden 2 Artikel gefunden!
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Filorexant
Artikelnummer: Cay29490-10
Filorexant is a dual antagonist of orexin 1 receptor (OX1R) and OX2R (Kis = 2.5 and 0.31 nM, respectively, for the recombinant human receptors). It selectively inhibits OX1R and OX2R over a panel of more than 170 receptors and enzymes. Filorexant inhibits orexin A-induced calcium mobilization in CHO cells expressing...
| Schlagworte: | [(2R,5R)-5-[[(5-fluoro-2-pyridinyl)oxy]methyl]-2-methyl-1-piperidinyl][5-methyl-2-(2-pyrimidinyl)phenyl]-methanone |
| Anwendung: | Orexin (OX1R / OX2R) receptor dual antagonist |
| CAS | 1088991-73-4 |
| MW: | 420.5 D |
ab 218,00 €
Filorexant
Artikelnummer: TGM-T16096-100mg
Description: Filorexant (MK-6096) is an orally bioavailable, effective, and selective reversible antagonist of OX1 and OX2 receptors, with (Ki <3 nM). Target: OX Receptor. Smiles: C[C@@H]1CC[C@@H](COc2ccc(F)cn2)CN1C(=O)c1cc(C)ccc1-c1ncccn1. References: Winrow CJ, et al. Pharmacological characterization of MK-6096 -...
| Schlagworte: | MK-6096 |
| Anwendung: | Hypnotic, Orexin receptor antagonist |
| CAS | 1088991-73-4 |
| MW: | 420.48 D |
ab 30,00 €
