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TMCB
Artikelnummer: Cay27652-10
TMCB is a dual inhibitor of casein kinase 2 (CK2) and ERK8 (IC50 = 0.5 µM for both). It also binds to Pim-1, HIPK2, and DYRK1A (Kis = 8.65, 15.25, and 11.9 µM, respectively) and inhibits greater than 50% of the activity of five kinases, including CK2, ERK8, and DYRK2, in a panel of 78 kinases at 10 µM. TMCB induces...
| Schlagworte: | 4,5,6,7-tetrabromo-2-(dimethylamino)-1H-benzimidazole-1-acetic acid |
| Anwendung: | CK2 / ERK8 dual inhibitor |
| CAS | 1085822-09-8 |
| MW: | 534.8 D |
ab 85,00 €
CK2/ERK8-IN-1
Artikelnummer: TGM-T10827-10mg
Description: CK2/ERK8-IN-1 (TMCB) is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 µM) and ERK8 (IC50s: 0.50 µM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 µM, 11.9 µM, and 15.25 µM). Target: Casein Kinase, DYRK, ERK, Apoptosis, Pim. Smiles:...
| Schlagworte: | TMCB |
| CAS | 1085822-09-8 |
| MW: | 534.82 D |
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