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Tafenoquine
Artikelnummer: TGM-T13083-10mg
Description: Tafenoquine is an 8-aminoquinoline,and is an agent of anti-malarial prophylactic. Target: Others. Smiles: O(C=1C2=C(C(NC(CCCN)C)=CC1OC)N=C(OC)C=C2C)C3=CC(C(F)(F)F)=CC=C3. References: Marcsisin SR, et al. Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the...
| Schlagworte: | WR 238605 |
| Anwendung: | Antimalarial |
| CAS | 106635-80-7 |
| MW: | 463.49 D |
ab 192,00 €
Tafenoquine
Artikelnummer: Cay30673-10
Tafenoquine is an aminoquinoline antimalarial agent. It is active against multidrug-resistant clinical isolates of P. falciparum (IC50s = 64.6-110.4 ng/ml). Tafenoquine (25 or 50 mg/kg) inhibits sporozoite transmission to mosquitos fed on P. berghei-infected mice. It also suppresses parasitemia in a hamster model of...
| Schlagworte: | WR 238605, N4-[2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl]-1,4-pentanediamine |
| Anwendung: | Antimalarial agent |
| CAS | 106635-80-7 |
| MW: | 463.5 D |
ab 106,00 €
