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PhIP
PhIP

Artikelnummer: TGM-T16525-100mg

Description: PhIP is a heterocyclic aromatic amine (HAA) from cooked meat. It belongs to pyridine heterocyclic amine and is a 2B carcinogen with estrogen activity. PhIP forms adducts with DNA that promote cancer. Target: Others. Smiles: Cn1c(N)nc2ncc(cc12)-c1ccccc1. References: Bellamri M, et al. Metabolic...
CAS 105650-23-5
MW: 224.26 D
ab 134,00 €
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2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Artikelnummer: Cay22590-10

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a food-derived carcinogen that is found in high temperature-cooked fish and meat. In humans, PhIP is metabolized by the cytochrome (CYP) P450 isoform CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form...
Schlagworte: PhIP, 1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine
Anwendung: Cooked meat carcinogen
CAS 105650-23-5
MW: 224.3 D
ab 39,00 €
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