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AZD 8329
Artikelnummer: Cay45334-1
An 11beta-HSD1 inhibitor (IC50 = 9 nM for the human enzyme), selective for 11beta-HSD1 over 11beta-HSD2 and 17beta-HSD1 (IC50s = >30 µM for both), and over 17beta-HSD3 with less than 5% inhibition at 10 µM, prevents impairments in cardiac function in a minipig model of myocardial infarction at 50 mg/kg per day,...
| Schlagworte: | 4-[5-(1,1-dimethylethyl)-4-[(tricyclo[3.3.1.13,7]dec-2-ylamino)carbonyl]-1H-pyrazol-1-yl]-benzoic acid |
| Anwendung: | 11beta-HSD1 inhibitor |
| CAS | 1048668-70-7 |
| MW: | 421.54 D |
ab 39,00 €
AZD8329
Artikelnummer: TGM-T14383-100mg
Description: AZD8329 is a selective and potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitor that inhibits 11beta-HSD2, 17beta-HSD1, 17beta-HSD3, and can be used for the study of allergic reactions in humans. Target: Dehydrogenase. Smiles:...
| Schlagworte: | AZD 8329, AZD-8329 |
| CAS | 1048668-70-7 |
| MW: | 421.53 D |
ab 79,00 €
