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JNJ-39758979
Artikelnummer: Cay41084-10
JNJ-39758979 is a histamine H4 receptor antagonist (Ki = 12.5 nM for the human receptor). It is selective for the histamine H4 receptor over histamine H1, H2, and H3 receptors (Kis = >1,000, >1,000, and 1,043 nM, respectively, for the human receptors), as well as 48 other receptors, ion channels, and transporters at...
| Schlagworte: | 4-[(3R)-3-amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyrimidinamine |
| Anwendung: | Histamine H4 receptor antagonist |
| CAS | 1046447-90-8 |
| MW: | 221.3 D |
ab 129,00 €
JNJ-39758979
Artikelnummer: TGM-T11723L-100mg
Description: JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. Target: Histamine...
| CAS | 1046447-90-8 |
| MW: | 221.3 D |
ab 67,00 €
