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RVX-208
RVX-208

Artikelnummer: Cay16424-1

The bromodomain and extra terminal (BET) proteins interact with acetylated lysine-containing sequences on target proteins via their bromodomains, commonly altering gene transcription. The human BET proteins contain two bromodomains, the first (BD1) being closer to the N-terminus than the second (BD2). RVX-208 is a...
Schlagworte: 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinazolinone
Anwendung: BET bromodomain BD2 antagonist
CAS 1044870-39-4
MW: 370.4 D
ab 61,00 €
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Apabetalone
Apabetalone

Artikelnummer: TGM-T2480-100mg

Description: Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary artery disease. Target: Epigenetic Reader Domain, HIV Protease. Smiles: COc1cc(OC)c2c(c1)[nH]c(nc2=O)-c1cc(C)c(OCCO)c(C)c1. References: Picaud S, et al....
Schlagworte: RVX-208, RVX000222
Anwendung: Targets bromodomain-containing protein 2 (BRD2)
CAS 1044870-39-4
MW: 370.4 D
ab 40,00 €
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