Zu "1038915-73-9" wurden 3 Artikel gefunden!
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MK-4827 (tosylate)
Artikelnummer: Cay20842-5
MK-4827 is an orally bioavailable inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s = 3.8 and 2.1 nM, respectively). It inhibits the proliferation of cancer cells carrying the breast cancer mutations BRCA1 and BRCA2 in vitro (IC50 values range from 10-100 nM) and has efficacy alone against a...
| Schlagworte: | Niraparib tosylate, 2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxamide, 4-methylbenzenesulfonate |
| Anwendung: | Antineoplastic |
| CAS | 1038915-73-9 |
| MW: | 492.6 D |
ab 62,00 €
MK-4827 tosylate
Artikelnummer: CDX-M0565-M010
White to off-white solid. Soluble in DMSO or DMF (both 20mg/ml). Sparingly soluble in ethanol (1mg/ml) or water (<1mg/ml). Chemical. CAS: 1038915-73-9. Formula: C19H20N4O . C7H8O3S. MW: 492.6. Synthetic. MK-4827 is an orally bioavailable inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s=3.8 and...
| Schlagworte: | Niraparib tosylate, (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4 methylbenzenesulfonate |
| CAS | 1038915-73-9 |
| MW: | 492,6 D |
ab 244,00 €
Niraparib, p-Toluenesulfonate Salt
Artikelnummer: LC-N-5688_100mg
Soluble in DMSO. Niraparib enhanced radiation-induced cytotoxicity in neuroblastoma cells. In vivo treatment with niraparib and radiation prolonged survival of mice in a murine xenograft model of metastatic neuroblastoma when compared to single modalities. Mueller S., et al. 'Poly (ADP-Ribose) polymerase inhibitor...
| Schlagworte: | MK-4827 |
| Anwendung: | Antineoplastic, PARP inhibitor |
| CAS | 1038915-73-9 |
| MW: | 492.59 D |
ab 86,00 €
