Zu "1037792-44-1" wurden 2 Artikel gefunden!
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MBX-2982
Artikelnummer: Cay22206-5
MBX-2982 is an agonist of GPR119. It reduces nuclear and total protein levels of sterol regulatory element binding protein 1 (SREBP-1) in HepG2 cells and rat primary hepatocytes under high-glucose and -insulin conditions and increases phosphorylation of the inhibitory form, SREBP-1c. MBX-2982 (10 mg/kg) inhibits...
| Schlagworte: | 5-ethyl-2-[4-[4-[[4-(1H-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-pyrimidine |
| Anwendung: | GPR119 agonist |
| CAS | 1037792-44-1 |
| MW: | 448.5 D |
ab 228,00 €
MBX-2982
Artikelnummer: TGM-T1793-100mg
Description: MBX-2982 is a selective, orally available GPR119 agonist used in the treatment of diabetes. Target: GPR. Smiles: CCc1cnc(nc1)N1CCC(CC1)c1ncc(COc2ccc(cc2)-n2cnnn2)s1. References: Hothersall JD, et al. Sustained wash-resistant receptor activation responses of GPR119 agonists. Eur J Pharmacol. 2015 Sep...
| Anwendung: | GPR119 agonist |
| CAS | 1037792-44-1 |
| MW: | 448.54 D |
ab 44,00 €
