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Gimeracil
Gimeracil

Artikelnummer: Cay16525-100

Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase (DYPD, Ki = 0.36 µM), the rate limiting enzyme in the catabolism of pyrimidines, including 5-fluorouracil (5-FU, Cay-14416). It inhibits the degradation of 5-FU in rat liver extracts (IC50 = 0.1 µM). Gimeracil inhibits homologous recombination and enhances...
Schlagworte: 5-Chlorodihydropyrimidine, CDHP, Gimestat, 5-chloro-4-hydroxy-2(1H)-pyridinone
Anwendung: Dihydropyrimidine dehydrogenase inhibitor
CAS 103766-25-2
MW: 145.5 D
ab 58,00 €
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Gimeracil
Gimeracil

Artikelnummer: CDX-G0209-G001

White to yellow crystalline powder. Soluble in DMSO (25mg/ml) or DMF (20mg/ml). Chemical. CAS: 103766-25-2. Formula: C5H4ClNO2. MW: 145.54. Gimeracil is an orally active inhibitor against dihydropyrimidine dehydrogenase (DPYD), the rate limiting enzyme for the catabolism of pyrimidines, including the...
Schlagworte: 5-Chloro-4-hydroxy-2(1H)-pyridinone, 5-Chloro-2,4-dihydroxypyridine, 5-Chloro-4-hydroxy-2-pyridone, Gimestat, CDHP
CAS 103766-25-2
MW: 145,54 D
ab 77,00 €
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Gimeracil
Gimeracil

Artikelnummer: TGM-T0987-100mg

Description: Gimeracil (Gimestat) is a competitive, reversible inhibitor of dihydropyrimidine dehydrogenase. Target: Autophagy. Smiles: OC=1C(Cl)=CNC(=O)C1. References: Prescrire Int. 2013 May,22(138):122.
Schlagworte: Gimestat
CAS 103766-25-2
MW: 145.54 D
ab 30,00 €
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