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Farudodstat
Artikelnummer: TGM-T10384-100mg
Description: Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity, showing potential as a first-in-class candidate in AML [Acute Myeloid Leukemia]. Target: DNA/RNA Synthesis, Apoptosis, Dehydrogenase. Smiles:...
| Schlagworte: | ASLAN003 |
| CAS | 1035688-66-4 |
| MW: | 356.32 D |
ab 43,00 €
ASLAN003
Artikelnummer: Cay33516-10
ASLAN003 is an inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 35 nM). It inhibits the proliferation of MOLM-14 and KG-1 acute myeloid leukemia (AML) cells (IC50s = 0.582 and 0.382 µM, respectively), as well as induces apoptosis in the same cells when used at concentrations of 0.5 and 1 µM. ASLAN003 (1, 2,...
| Schlagworte: | 2-[(3,5-difluoro-3'-methoxy[1,1'-biphenyl]-4-yl)amino]-3-pyridinecarboxylic acid |
| Anwendung: | DHODH inhibitor |
| CAS | 1035688-66-4 |
| MW: | 356.3 D |
ab 61,00 €
