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Telotristat
Artikelnummer: TGM-T21506-100mg
Description: Telotristat is the active metabolite of LX1606(Telotristat etiprate), which is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor and shows potential antiserotonergic activity. Target: Hydroxylase. Smiles: Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)-c1ccc(C[C@H](N)C(O)=O)cc1)C(F)(F)F....
| CAS | 1033805-28-5 |
| MW: | 546.93 D |
ab 31,00 €
Telotristat
Artikelnummer: Cay29424-10
Telotristat is a tryptophan hydroxylase 1 (TPH1) inhibitor (IC50 = 16 nM). Dietary administration of telotristat to pregnant and lactating mice decreases serotonin (5-HT, Cay-14332) levels in maternal serum and decreases the femoral bone volume to tissue volume ratio, trabecular number and thickness, and cortical...
| Schlagworte: | LP778902,... |
| Anwendung: | TPH1 inhibitor |
| CAS | 1033805-28-5 |
| MW: | 546.9 D |
ab 117,00 €
