Zu "1032823-75-8" wurden 2 Artikel gefunden!
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GSK1292263
Artikelnummer: Cay26181-5
GSK1292263 is an agonist of G protein-coupled receptor 119 (GPR119, EC50 = 43.9 nM in CHO-K1 cells expressing human receptors). It inhibits increases in sterol regulatory element binding protein-1 (SREBP-1) levels induced by the LXR agonist T0901317 and increases activation of AMPK in HepG2 cells in a...
| Schlagworte: | 5-[[1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl]methoxy]-2-[4-(methylsulfonyl)phenyl]-pyridine |
| Anwendung: | GPR119 agonist |
| CAS | 1032823-75-8 |
| MW: | 456.6 D |
ab 183,00 €
GSK1292263
Artikelnummer: TGM-T2701-100mg
Description: GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2. Target: GPR. Smiles: CC(C)c1noc(n1)N1CCC(COc2ccc(nc2)-c2ccc(cc2)S(C)(=O)=O)CC1. References: Zhu X, et al. Eur J Med Chem, 2011, 46(7), 2901-2907.
| CAS | 1032823-75-8 |
| MW: | 456.56 D |
ab 29,00 €
