Zu "1032754-93-0" wurden 4 Artikel gefunden!
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GDC-0980
Artikelnummer: LKT-G1209.5
GDC-0980 is an inhibitor of PI3K and mTORC1/2 that exhibits anticancer chemotherapeutic and anti-angiogenic activities. GDC-0980 inhibits cell growth in uterine serous carcinoma cells and decreases vascular density by altering vascular permeability parameter K (trans) in other cellular models. GDC-0980 inhibits cell...
| Schlagworte: | RG7422 |
| Anwendung: | PI3K / mTOR inhibitor |
| CAS | 1032754-93-0 |
| MW: | 498.6 D |
ab 164,00 €
GDC-0980
Artikelnummer: Cay18303-1
GDC-0980 is a potent inhibitor of class I phosphatidylinositol 3-kinase (PI3K) isoforms, with IC50 values of 5, 27, 7, and 14 nM for PI3Kalpha, beta, delta, and gamma, respectively, in cell-free assays. It also inhibits mTOR (Ki = 17 nM) but is inactive against a large panel of additional kinases. GDC-0980 induces...
| Schlagworte: | Apitolisib, RG7422,... |
| Anwendung: | PI3K inhibitor |
| CAS | 1032754-93-0 |
| MW: | 498.6 D |
ab 97,00 €
RG-7422
Artikelnummer: SYN-1150-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. GDC-0980 (RG7422) is a selective, dual PI3 Kinase and mTOR Kinase inhibitor with IC(50) values of 5, 27, 7, and 14nM for PI3Kalpha-delta respectively. It inhibits mTOR with a Ki of 17nM. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Schlagworte: | GDC-0980 |
| Anwendung: | PI3K / mTOR inhibitor |
| CAS | 1032754-93-0 |
| MW: | 498,6 D |
ab 154,00 €
Apitolisib
Artikelnummer: TGM-T1916-100mg
Description: Apitolisib (RG 7422), an effective, class I PI3K inhibitor for PI3Kalpha(IC50=5 nM), PI3Kbeta(IC50=27 nM), PI3Kdelta(IC50=7 nM), PI3Kgamma (IC50=14 nM), is used in trials study of solid cancers, breast cancer, prostate cancer, renal cell carcinoma, and endometrial carcinoma, among others. Target:...
| Schlagworte: | RG 7422, GNE 390, GDC-0980 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 1032754-93-0 |
| MW: | 498.6 D |
ab 37,00 €
