Zu "1026785-59-0" wurden 2 Artikel gefunden!
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Lomibuvir
Artikelnummer: Cay26630-10
Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV, Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM).Formal Name:...
| Schlagworte: | VX-222,... |
| Anwendung: | Antiviral, NS5B polymerase inhibitor |
| CAS | 1026785-59-0 |
| MW: | 445.6 D |
ab 181,00 €
cis-Lomibuvir
Artikelnummer: TGM-T73814-10mg
Description: Cis-Lomibuvir (cis-VX-222), a cis-isomer of Lomibuvir, is a selective non-nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase (RdRp), targeting thumb pocket 2 with a dissociation constant (Kd) of 17 nM. It exhibits an EC50 of 5.2 nM against the 1b/Con1 HCV subgenomic replicon,...
| Anwendung: | Antiviral, NS5B polymerase inhibitor |
| CAS | 1026785-59-0 |
| MW: | 445.61 D |
ab 788,00 €
