Zu "1026582-88-6" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
RO-3
Artikelnummer: TGM-T5513-100mg
Description: RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor. Target: P2X Receptor. Smiles: COc1cc(Cc2cnc(N)nc2N)c(cc1OC)C(C)C. References: Gever J R , Cockayne D A , Dillon M P , et al. Pharmacology of P2X channels[J]. Pflügers Archiv European Journal of Physiology, 2006, 452(5):513-37.
| Anwendung: | Purinergic receptor P2X3 /P2X2/3 dual antagonist |
| CAS | 1026582-88-6 |
| MW: | 302.37 D |
ab 48,00 €
RO-3
Artikelnummer: Cay29635-10
RO-3 is a dual antagonist of the purinergic receptor subtypes P2X3 and P2X2/3 (IC50s = 0.1 and 1.26 µM, respectively). It is selective for P2X3 and P2X2/3 over P2X1, P2X2, P2X4, P2X5, and P2X7 receptors (IC50s = >10 µM for all) but is an antagonist of ML1-type melatonin receptors (IC50 = 0.398 µM).Formal Name:...
| Schlagworte: | 5-[[4,5-dimethoxy-2-(1-methylethyl)phenyl]methyl]-2,4-pyrimidinediamine |
| Anwendung: | Purinergic receptor P2X3 /P2X2/3 dual antagonist |
| CAS | 1026582-88-6 |
| MW: | 302.4 D |
ab 111,00 €
