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BMS-777607
Artikelnummer: Cay18517-1
BMS-777607 is an inhibitor of the Met kinase family. It inhibits Ron, Met, Tyro-3, and AxI with IC50 values of 1.8, 3.9, 4.3, and 1.1 nM, respectively. At higher concentrations it is reported to inhibit Mer, FLT3, Aurora B, Lck, and VEGFR2 (IC50s = 14, 16, 78, 120, and 180 nM, respectively). In cancer cells,...
| Schlagworte: | BMS-817378,... |
| Anwendung: | Ron, Met, Tyro3, AxI inhibitor |
| CAS | 1025720-94-8 |
| MW: | 512.9 D |
ab 56,00 €
BMS 777607
Artikelnummer: TGM-T2699-100mg
Description: BMS 777607 (BMS 817378) is a Met-related inhibitor targeting c-Met, Axl, Ron, and Tyro3 with IC50 values of 3.9 nM, 1.1 nM, 1.8 nM, and 4.3 nM, respectively. BMS-777607 has been investigated in basic science research for malignant solid tumors. Target: c-Met/HGFR, TAM Receptor. Smiles:...
| Schlagworte: | BMS777607 , BMS-777607 , BMS 817378 |
| CAS | 1025720-94-8 |
| MW: | 512.89 D |
ab 30,00 €
