Zu "1025687-58-4" wurden 3 Artikel gefunden!
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R788 disodium salt
Artikelnummer: SYN-1122-M001
Slightly soluble (<1mg/ml) in DMSO or ethanol. Tamatinib effectively inhibits BCR signaling in vivo, resulting in reduced proliferation and survival of the malignant B cells and significantly prolonged survival of the treated animals. Target: BCR , Kinase Group: PTK , Substrate: Tyrosine
| Schlagworte: | Fostamatinib, Tamatinib fosdium, FosD, R-788 |
| Anwendung: | Syk inhibitor |
| CAS | 1025687-58-4 |
| MW: | 624,5 D |
ab 162,00 €
R788 (sodium salt)
Artikelnummer: Cay18501-5
R788 is a prodrug of R406 (Cay-11422), an inhibitor of Syk (Ki = 30 nM). R788 conversion to the biologically active R406 is catalyzed by the action of alkaline phosphatases present on the apical brush-border of the membranes of intestinal enterocytes. It produces anti-inflammatory and immunomodulating effects by...
| Schlagworte: | Fostamatinib, NSC 745942, R935788, Tamatinib Fosdium,... |
| Anwendung: | Syk inhibitor/R406 prodrug |
| CAS | 1025687-58-4 |
| MW: | 624.42 D |
ab 67,00 €
Fostamatinib Disodium
Artikelnummer: TGM-T2605-100mg
Description: Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulatory activities. Target: FLT, Syk. Smiles: [Na+].[Na+].COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)N(COP([O-])([O-])=O)c4n3)n2)cc(OC)c1OC. References: Braselmann S, et al. J...
| Schlagworte: | R788 Disodium, R788 (Fostamatinib) Disodium, R788(Disodium), Tamatinib Fosdium |
| Anwendung: | R406 prodrug, Syk inhibitor |
| CAS | 1025687-58-4 |
| MW: | 624.42 D |
ab 38,00 €
